(1) It is also necessary to exclude reversible causes of failure of brain function, including depressant drugs and hypothermia.(2) Users often present with multiple drug ingestions, which may include stimulant and depressant drugs.(3) The drug is a depressant and will lead to lack of energy and general relaxation of the muscles.(4) The interactions of carisoprodol with other CNS depressant drugs appears to be particularly significant.(5) These data underscore the need for clinicians to search for problems with other depressant drugs and to take care before prescribing benzodiazepines in alcohol-dependent individuals.(6) The debate, in other words, boils down to whether or not the stimulus of increased government spending has a stronger effect on the economy in the short term than the depressant of higher interest rates.(7) The independence wars' impact has generally been seen as a depressant on economic activity, resulting in a general stagnation that lasted until at least mid-century, with a few exceptions.(8) Alcohol is a depressant , a powerful drug with mood-altering effects.(9) He argues that, despite the severe strain on population and economic growth caused by the slave trade, the economy continued to expand from the seventeenth to the nineteenth century, and the colonial state acted as an economic depressant rather than a stimulant.(10) LSD effects appear to be totally different from those produced by narcotics or other depressant drugs.(11) The report also suggests that the number of new users has been climbing since the mid-1980s, the largest increase occurring with the depressants oxycodone, methadone and morphine.(12) Phenothiazines, tricyclic antidepressants, and CNS depressants may potentiate the therapeutic and adverse effects of opioids.(13) Interactions with benzodiazepines, pentobarbital, and other central nervous system depressants can yield additional sedative effects.