
A hydrogen atom, H,
plus pigs MINUS P, "higs."
The Big Bang Theory Season 3, Episode 13

The answer is MINUS eight pi alpha.
The Big Bang Theory Season 1, Episode 13

Minus.
The Big Bang Theory Season 6, Episode 6

...MINUS 21 men
before the loss of virginity...
The Big Bang Theory Season 4, Episode 1

T Minus 45 seconds!
The Big Bang Theory Season 7, Episode 14